Dataset: Sycon Transcriptom Data - Regulatory RNA and the origin of multicellularity, 2013

Abstract

"Sycon Transcriptom Data, 2013" is part of the project "Regulatory RNA and the Origin of Multicellularity".  
One of the most important evolutionary transitions in the history of life was the evolution of multicellular animals and fungi from unicellular eukaryotes. Despite this transition has been one of the most complex and profound among eukaryotes, the underlying genetic changes of this giant leap in evolution are very much unclear. In contrast to earlier works, which focused on changes of protein coding genes, we are in the proposed project investigating alteration of gene regulation by means of small regulatory RNAs. In recent years we have seen an increased awareness of noncoding RNA in animals and fungi. These function as regulators of gene expression, which have been found to be important for embryonic stem cell differentiation, cell proliferation, apoptosis and metabolic regulation. Hence, small regulatory RNA is vital for the development of complex body plans. A few non-coding RNAs have also been identified in premetazoan and prefungal eukaryotes, but as only a few species have so far been investigated, it is still a big gap in our knowledge of the processes underlining the evolution of animal and fungal multicellularity. This project aims at investigating the role of regulatory RNA in the evolution of multicellularity by comparing the genomes and RNA repertoire in unicellular relatives of animals and fungi (i.e. Choanozoa). As these two groups evolved multicellularity independently from different unicellular ancestors, these comparisons will reveal lineage specific changes such as gene losses, expansions, lateral gene transfers and functional changes. The requested project will apply a combination of bioinformatic and RNA sequencing approaches to obtain a comprehensive understanding of the diversity and evolution of regulatory RNA elements within Choanozoa and thereby also its contribution to the evolution of multicellularity.

The data in this project are used in published articles. The data are available through databases.

Variable Groups

Full Title

Sycon Transcriptom Data - Regulatory RNA and the origin of multicellularity, 2013

Identification Number

NSD2272

Authoring Entity

Name Affiliation
Bråte, Jon Department of Biosciences, University of Oslo

Producer

Name Affiliation Abbreviation Role
Bråte, Jon Department of Biosciences, University of Oslo IBV, UiO Principal Investigator

Copyright

Copyright (C) 2013 Jon Bråte, Department of Biosciences, UiO

Funding Agency/Sponsor

Name Abbreviation Role Grant
The Research Council of Norway RCN 213707

Data Distributor

Name Affiliation Abbreviation
NSD - Norwegian Centre for Research Data NSD

Version

Date: 2015-12-12

Notes

Original data from Jon Bråte, Department of Biosciences, UiO are documented and prepared, first NSD-version.

Bibliographic Citation

"Sycon Transcriptom Data - Regulatory RNA and the origin of multicellularity, 2013". Data collected by Jon Bråte, Department of Biosciences, UiO. First NSD edition, Bergen 2015.

List of Keywords

Topic Classification

Time Period Covered

Start End Cycle
2012-08-01 2015-07-31

Date of Collection

Start End Cycle
2012-08-01 2015-07-31

Country

Norway  (NO)

Unit of Analysis

Other

Universe

Transcriptom from the calcareous sponge Sycon ciliatum.

Kind of Data

Other

Time Method

Cross-sectional survey

Data Collector

Sampling Procedure

The sponges were collected off the coast of Bergen, and the data are generated in cooperation with Maja Adamska at the Sars Centre in Bergen.

Mode of Data Collection

Other

Location

Availability Status

Data are freely available for downloading.

Restrictions

Data are freely available for downloading.

Related Publications

Developmental Gene Expression Provides Clues to Relationships Between Sponge and Eumetazoan Body Plans

Leininger, S., Adamski, M., Bergum, B., Guder, C., Liu, J., Laplante, M., Bråte, J., Hoffmann, F., Fortunato, S., Jordal, S., Rapp, H.T., Adamska, M. (2014) “Developmental gene expression provides clues to relationships between sponge and eumetazoan body plans” in Nature Communications 5, 3905

The data are available through The European Bioinformatics Institute (Part of the European Molecular Biology Laboratory) by using the codes: E-MTAB-2430 and E-MTAB-2431.

Regulatory RNA at the Root of Animals: Dynamic Expression of Developmental LincRNAs in the Calcisponge Sycon Ciliatum

Bråte J, Adamski M, Neumann RS, Shalchian-Tabrizi K, Adamska M. (2015). Regulatory RNA at the Root of Animals: Dynamic Expression of Developmental LincRNAs in the Calcisponge Sycon Ciliatum. Proc. R. Soc. B. 20151746.

The data are available through Dryad Digital Repository by using the code: doi:10.5061/dryad.v83fj.

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