Dataset: Regulation of Chromatin Remodeling and Gene Activity by A-kinase Anchoring Proteins, 2015

Abstract

The goal of this project was to characterize in detail the molecular function of the nuclear AKAP, AKAP95, on the regulation of chromatin remodeling and gene activity in a differentiation context. The experimental strategy combined stem cell differentiation with state-of-the-art genome-scale epigenetics and bioinformatics, functional chromatin-based assays and RNAi/mutant. The data includes:  
- AKAP and FUS_genomics: Genomics viewer (browser) files and peak analysis for AKAP95 and FUS  
- AKAP and TPR: Images, microsopy videos, analyses, text/observations, manuscript. Data on BioID experiments and analysis  
- AKAP ChIP data and analysis. ChIP data_browser folder: genomics data for genome browsing (viewing). Analysis folder: various datasets. AKAP95ChIPGeneNames folder: gene lists  
- BioID: Mass-spectrometry proteomics data files  

For access to the dataset, use the NSD application form:  

http://www.nsd.uib.no/nsd/english/orderform.html

Variable Groups

Full Title

Regulation of Chromatin Remodeling and Gene Activity by A-kinase Anchoring Proteins, 2015

Identification Number

NSD2340

Authoring Entity

Name Affiliation
Collas, Phillippe Institute of Basic Medical Sciences, University of Oslo

Producer

Name Affiliation Abbreviation Role
Collas, Phillip Institute of Basic Medical Sciences, University of Oslo UiO Principal Investigator

Copyright

Copyright (C) 2015 Phillippe Collas, Institute of Basic Medical Sciences, UiO

Funding Agency/Sponsor

Name Abbreviation Role Grant
The Research Council of Norway RCN 204605

Data Distributor

Name Affiliation Abbreviation
NSD – Norwegian Centre for Research Data NSD

Version

Date: 2016-08-30

Notes

Original data from Phillippe Collas, Institute of Basic Medical Sciences, University of Oslo are documented and prepared, first NSD-version.

Bibliographic Citation

"Regulation of Chromatin Remodeling and Gene Activity by A-kinase Anchoring Proteins, 2015". Data collected by Phillippe Collas, Institute of Basic Medical Sciences, University of Oslo. First NSD edition, Bergen 2016.

List of Keywords

Topic Classification

Time Period Covered

Start End Cycle
2011 2015

Date of Collection

Start End Cycle
2012-04-01 2015-12-31

Country

Norway  (NO)

Geographic Coverage

Country

Unit of Analysis

Other

Kind of Data

Other

Time Method

Cross-sectional survey

Data Collector

Collas, Phillippe, Institute of Basic Medical Sciences, University of Oslo  (UiO)

Sampling Procedure

Data generated in the project included microscopy video, bio-chemical data, genomics data (ChIP), text and photos. Data was generated by microscopy and bio-chemical experiments and bioinformatics analysis.

Mode of Data Collection

Other

Location

Availability Status

NSD can make data from "Regulation of Chromatin Remodeling and Gene Activity by A-kinase, 2015" available after 01.01.2021. The data will be available for research, teaching and students when ordered.

Extent of Collection

80 data files; different formats can be made.

Restrictions

NSD can make data from "Regulation of Chromatin Remodeling and Gene Activity by A-kinase Anchoring Proteins, 2015" available after 01.01.2021. The data will be available for research, teaching and students when ordered.

Citation Requirement

Users are obliged to refer to producer and distributor of the data by writing the following in forewords or footnotes in eventual publications:
"(Some of) the data applied in the analysis in this publication are based on "Regulation of Chromatin Remodeling and Gene Activity by A-kinase Anchoring Proteins, 2015". The survey was financed by The Reasearch Council of Norway. The data are provided by Phillippe Collas, Institute of Basic Medical Sciences, University of Oslo (UiO) and prepared and made available by NSD – Norwegian Centre for Research Data. Neither Phillippe Collas, Institute of Basic Medical Sciences, UiO, The Research Council of Norway nor NSD are responsible for the analysis/interpretation of the data presented here.

Deposit Requirement

Access to data is given on the condition that NSD gets a PDF-file of eventual reports that are written on the basis of the data. This to ensure best possible information of the use of data we distribute.

Conditions

The order form has to include name, institutional affiliation, project title, information about sources of financing and postal address. A declaration of secrecy has to be signed before delivery of data.

Disclaimer

Neither Phillippe Collas, Institute of Basic Medical Sciences, UiO, The Research Council of Norway nor NSD are responsible for the analysis/interpretation of the data presented here.

Related Publications

AKAP95 targets nucleoporin TPR in mitosis and is important for the mitotic spindle checkpoint

López-Soop G, Rønningen T, Thiede B, Collas P, Küntziger T. (2016) AKAP95 targets nucleoporin TPR in mitosis and is important for the mitotic spindle checkpoint. Mol Biol Cell (under re-review)

AKAP95 associates with the transcription factor FUS on at active loci

Lopez-Soop G, Shah A, Collas P, Küntziger T. AKAP95 associates with the transcription factor FUS on at active loci. (Manuscript under preparation)

Metadata Index

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