Dataset: Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015

Abstract

The study is a prospective controlled study of HIV seropositive patients investigating whether an anti-inflammatory COX-2 inhibitor (etoricoxib) given respectively 2 and 24 weeks improves the ability of the immune response against T cell-dependent vaccines in in proportion to a control group. The project will also examine (i) effects on HIV-associated chronic immune activation, one pathogenetic unfortunate "driver" of HIV infection associated with rapid progression of HIV and cardiovascular risk; (ii) effect on HIV-specific immunity.

Variable Groups

Full Title

Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015

Identification Number

NSD2268

Authoring Entity

Name Affiliation
Kvale, Dag Division of Medicine, Oslo University Hospital

Producer

Name Affiliation Abbreviation Role
Kvale, Dag Division of Medicine, Oslo University Hospital OUS Primary Investigator

Copyright

Copyright (C) 2015 Dag Kvale, Division of Medicine, OUS

Funding Agency/Sponsor

Name Abbreviation Role Grant
The Research Council of Norway RCN 192514
Oslo University Hospital OUS

Data Distributor

Name Affiliation Abbreviation
Norwegian Social Science Data Services NSD

Version

Date: 2015-12-12

Notes

Original data from Dag Kvale, Division of Medicine, Oslo University Hospital are documented and prepared, first NSD-version.

Bibliographic Citation

"Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015". Data collected by Dag Kvale, Division of Medicine, Oslo University Hospital. First NSD edition, Bergen 2015.

List of Keywords

Topic Classification

Time Period Covered

Start End Cycle
2009 2014

Date of Collection

Start End Cycle
2011-01-12 2015-01-07

Country

Norway  (NO)

Geographic Coverage

Country

Unit of Analysis

Individual

Universe

Voluntary HIV-seropositive individuals who fill inclusion criteria and no exclusion criteria according to protocol.

Kind of Data

Clinical data

Data Collector

Kvale, Dag, Division of Medicine, Oslo University Hospital  (OUS)

Sampling Procedure

The sample is drawn from HIV-seropositive individuals who fill inclusion criteria and no exclusion criteria according to protocol.

Mode of Data Collection

Clinical measurements

Location

Availability Status

NSD can in agreement with the Principal Investigator make data from "Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015” available when ordered after 01.01.2019.

Extent of Collection

One data file; different formats can be made.

Restrictions

NSD can in agreement with the Principal Investigator make data from "Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015" available when ordered after 01.01.2019.

Citation Requirement

Users are obliged to refer to producer and distributor of the data by writing the following in forewords or footnotes in eventual publications:
"(Some of) the data applied in the analysis in this publication are based on "Improved Vaccination Responses and Optional Immunomodulating Therapy by Adjuvant Administration of COX-2 Inhibitor in HIV-infected Patients, 2015". The survey was financed by The Reasearch Council of Norway. The data are provided by Dag Kvale, Division of Medicine, Oslo University Hospital and prepared and made available by the Norwegian Social Science Data Services (NSD). Neither Dag Kvale, Division of Medicine, Oslo University Hospital, The Research Council of Norway nor NSD are responsible for the analysis/interpretation of the data presented here.

Deposit Requirement

Access to data is given on the condition that NSD gets a PDF-file of eventual reports that are written on the basis of the data. This to ensure best possible information of the use of data we distribute.

Conditions

The order form has to include name, institutional affiliation, project title, information about sources of financing and postal address. A declaration of secrecy has to be signed before delivery of data.

Disclaimer

Neither Dag Kvale, Division of Medicine, Oslo University Hospital, The Research Council of Norway nor NSD are responsible for the analysis/interpretation of the data presented here.

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